What is Rett Syndrome primarily categorized as?

Rett Syndrome is primarily categorized as a nervous system disorder that leads to developmental regression. This disorder predominantly affects females and is characterized by normal early growth and development followed by a loss of purposeful hand skills and spoken language. Children with Rett Syndrome often experience a range of cognitive, motor, and behavioral challenges as the disorder progresses, including repetitive hand movements, loss of social engagement, and overall developmental delays.

The nature of Rett Syndrome emphasizes its impact on the nervous system, particularly due to mutations in the MECP2 gene, which are instrumental in brain development and function. Understanding this classification helps in formulating appropriate interventions and supports tailored to the specific needs of children with Rett Syndrome.